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Data highlights

The Data Highlights section showcases recently published datasets on COVID-19 and SARS-CoV-2 by researchers affiliated with a Swedish research institute. The goal is to highlight openly shared data that can potentially be used by many other researchers to make further discoveries. If you have published or are about to publish data that you think should be highlighted in this section, get in touch with us.

Mechanism of entry used by human species D adenoviruses proving important for COVID-19 vaccine development
Mechanism of entry used by human species D adenoviruses proving important for COVID-19 vaccine development

2021-01-18

New study identifies a noncanonical entry mechanism used by human adenoviruses, important for development of adenovirus-based vaccine vectors. The reported X-ray structural data was made available through the Protein Data Bank.
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A novel approach to discover and characterize broad-spectrum antivirals
A novel approach to discover and characterize broad-spectrum antivirals

2020-12-18

Newly discovered antiviral compounds showed broad-range antiviral activity against pathogenic RNA viruses such as SARS-CoV-2. The authors share data freely in open repositories.
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Pathogenesis of hyperinflammatory syndrome associated with COVID-19 in children
Pathogenesis of hyperinflammatory syndrome associated with COVID-19 in children

2020-12-07

Multiple autoantibodies and specific cytokines could be involved in the pathogenesis of MIS-C associated with COVID-19. Data and code made available in open repositories.
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An alpaca-derived nanobody can potently neutralize SARS-CoV-2
An alpaca-derived nanobody can potently neutralize SARS-CoV-2

2020-11-27

Leo Hanke and colleagues identified a SARS-CoV-2 RBD-specific single domain antibody fragment, Ty1, that potently neutralizes the virus. Ty1 should now be further investigated as a candidate for antiviral therapy.
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Synthetic nanobodies are easy to produce and can effectively neutralize SARS-CoV-2
Synthetic nanobodies are easy to produce and can effectively neutralize SARS-CoV-2

2020-11-24

Recently published study demonstrates that it is possible to select highly specific binders with neutralizing activity against SARS-CoV-2 from a synthetic nanobody library in a short timeframe.
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MAIT cell activation and dynamics studied in relation to COVID-19 disease severity
MAIT cell activation and dynamics studied in relation to COVID-19 disease severity

2020-11-18

Tiphaine Parrot and colleagues studied changes in conventional and unconventional T cell subsets in patients with various disease severity using flow cytometry. The results were published along with the data.
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Crystal structure of SARS CoV-2 nsp-10 - a potential drug target for COVID-19
Crystal structure of SARS CoV-2 nsp-10 - a potential drug target for COVID-19

2020-11-03

A study by Rogstam and colleagues published along with the crystal structure of SARS CoV-2 non-structural protein 10 in the Protein Data Bank provides a starting point for structure-guided drug discovery and design.
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Bayesian model for estimating the impact of mobility patterns on COVID-19 infection
Bayesian model for estimating the impact of mobility patterns on COVID-19 infection

2020-10-23

Patrick Bryant and Arne Elofsson shared code and instructions for modelling COVID-19 development using MCMC simulations based on mobile phone mobility data from Google mobility reports.
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First study using data collected as part of the large-scale serology testing at SciLifeLab published
First study using data collected as part of the large-scale serology testing at SciLifeLab published

2020-10-15

This study used only a fraction of the large volume of serology data continuously collected by the ScilifeLab Autoimmunity and Serology profiling facility.
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Data-driven research shows that Neanderthal gene connected to severity of COVID-19
Data-driven research shows that Neanderthal gene connected to severity of COVID-19

2020-10-02

Study by Hugo Zeberg and Svante Pääbo fully based on openly available data published open access in Nature.
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Method circumventing RNA extraction in RT-PCR COVID-19 testing published along with data
Method circumventing RNA extraction in RT-PCR COVID-19 testing published along with data

2020-10-01

Study by Björn Reinius and co-workers published open access in Nature Communications along with source data and the computational code.
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Statistics on SARS-CoV-2 antibody tests carried out by SciLifeLab now available
Statistics on SARS-CoV-2 antibody tests carried out by SciLifeLab now available

2020-09-30

We are launching a page with statistics on the SARS-CoV-2 antibody tests carried out at the SciLifeLab Autoimmunity and Serology profiling facility.
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