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Overview of research projects on COVID-19 funded by major Swedish funding agencies

Last updated: 27.11.2020

This is a manually curated list of research projects on COVID-19 which are funded by major funding agencies in Sweden. New projects are added on an ongoing basis. If you would like your project to be listed here, please get in touch with us (datacentre@scilifelab.se). See also SweCRIS, a database of all funded research projects in Sweden, where it is possible to search using custom keywords.

A list of all ethically approved clinical studies on COVID-19 in Sweden up until October 2020 can be found here (only in Swedish).

Swedish Research Council

vr.se

Project title Principal investigator PI affiliation Duration
Glycan-based antivirals against SARS-CoV-2 and future pandemic viruses Niklas Arnberg Umeå University 2020-08-01 - 2020-12-31
Cellular-mediated immunity against SARS-CoV-2 Marcus Buggert Karolinska Institute 2020-08-01 - 2020-12-31
Organization and response to covid-19 of municipal health and social care of older people – impact on mortality and health care utilization in Region Stockholm Bo Burström Karolinska Institute 2020-08-01 - 2020-12-31
Convalescent plasma for treatment of COVID-19: A randomized controlled trial Joakim Dillner Karolinska Institute 2020-08-01 - 2020-12-31
Digital care and Covid-19: The scope for scaling up digital care in a time of an infectious pandemic in Sweden Björn Ekman Lund University 2020-08-01 - 2020-12-31
Collateral damage of COVID-19 in older adults: short and long-term health consequences of the epidemic outbreak Laura Fratiglioni Karolinska Institute 2020-08-01 - 2020-12-31
Targeting the most severely affected in the COVID-19 pandemic: older adults’ medications and other crucial factors in large nationwide data Kristina Johnell Karolinska Institute 2020-08-01 - 2020-12-31
Characterization of SARS-CoV-2 specific antibody and T cell responses over time after infection: predicting the future by understanding correlates to protection Jonas Klingström Karolinska Institute 2020-08-01 - 2020-12-31
Attenuation of SARS-CoV-2 infectivity and hyperinflammation in Covid-19 by heparin-related polysaccharides Jin-ping Li Uppsala University 2020-08-01 - 2020-12-31
Antibody specificities for protective immunity after Covid-19 vaccination Karin Loré Karolinska Institute 2020-08-01 - 2020-12-31
Effect of face-masks during air-borne pandemics from fluid mechanical aspects Staffan Lundström Luleå University of Technology 2020-08-01 - 2020-12-31
Exploring immunologic and genetic factors in COVID-19 with relevance for immunity and long-term health: a new BAMSE follow-up Erik Melén Karolinska Institute 2020-08-01 - 2020-12-31
Mechanistic and therapeutic studies of the innate immune response in human subjects with COVID-19 Bo Nilsson Uppsala University 2020-08-01 - 2020-12-31
Neutrophil Extracellular Traps as Potential Driver of COVID-19 Mia Phillipson Uppsala University 2020-08-01 - 2020-12-31
Covid-19 epidemic in Sweden and cardiometabolic disease: using available data from Swedish registers. Annika Rosengren University of Gothenburg 2020-08-01 - 2020-12-31
Inhibiting Corona virus-RNA translation with existing antibiotics and other small molecules Suparna Sanyal Uppsala University 2020-08-01 - 2020-12-31
Evaporation dynamics of COVID-bearing droplets under different atmospheric conditions Gaetano Sardina Chalmers University of Technology 2020-08-01 - 2020-12-31
Diary of a pandemic: Monitoring of work-related stress symptoms among healthcare workers through a mobile application. Aleksandra Sjöström-Bujacz Karolinska Institute 2020-08-01 - 2020-12-31
Understanding respiratory and systemic immune responses during COVID-19: Implications for prediction of disease severity Anna Smed-Sörensen Karolinska Institute 2020-08-01 - 2020-12-31
Covid-19 and androgen deprivation therapy for prostate cancer. Populationbased studies Pär Stattin Uppsala University 2020-08-01 - 2020-12-31
A genetic trap for small molecule inhibitors of the SARS-CoV-2 main protease Per Sunnerhagen University of Gothenburg 2020-08-01 - 2020-12-31
Antival compunds against CoV-2 helicase Anders Sönnerborg Karolinska Institute 2020-08-01 - 2020-12-31
Intravenous immunoglobulin to dampen covid-induced cell damage and hyperinflammation Agnes Wold University of Gothenburg 2020-08-01 - 2020-12-31
Immunological correlates of protection in COVID-19 disease and after COVID-19 vaccination Anna Smed Sörensen Karolinska Institute 2021-01-01 - 2023-12-31
Stochastic modelling of epidemic outbreaks - post Covid-19 Tom Britton Stockholm University 2020-12-01 - 2024-11-30
Wuhan Interaction with Stockholm Evidence-based Research (WISER) project on health perspectives in the older population facing the SARS-CoV-2 outbreak Sara Hägg Karolinska Institute 2021-01-01 - 2023-12-31
Mucosal immunity against SARS-CoV-2 – an unexplored field Qiang Pan-Hammarström Karolinska Institute 2021-01-01 - 2023-12-31
Preventing paediatric pneumonia deaths in Nigeria Carina King Karolinska Institute 2020-12-01 - 2022-12-31
Interdisciplinary framework on the role of adaptive cellular immunity in SARS-CoV-2 protection Marcus Buggert Karolinska Institute 2021-01-01 - 2023-12-31

SciLifeLab / Knut and Alice Wallenberg Foundation

scilifelab.se / kaw.wallenberg.org

Project title Area Principal investigator PI affiliation Duration
Uppsala COVID-19 ICU Biobank Biobanks Michael Hultström Uppsala University 2020 - 2021
Building Capacity - the Sahlgrenska Covid-19 Biobank Biobanks Magnus Gisslén University of Gothenburg 2020 - 2021
COVID-UMU: Sample collection and understanding the transition from mild to severe COVID-19 Biobanks Clas Ahlm Umeå University 2020 - 2021
Assessment of SARS-CoV-2 specific antibodies in adults, and building a repository of samples from seroconverted asymptomatic adults Biobanks Åsa Torinsson Naluai University of Gothenburg 2020 - 2021
The spread of SARS-CoV-2 monitored by the serum samples routinely obtained through maternal screening and blood donor screening Biobanks Martin Sundqvist Örebro University 2020 - 2021
The COMMUNITY Study- COVID-19 Biomarker and Immunity Study Biobanks Charlotte Thålin Karolinska Institute / Danderyd Hospital 2020 - 2021
Establishing a biobank of clinical specimens for studying evolution of viral diversity and development of immune response, including inflammation, seroprevalence and protective antibodies, in SARS-Cov2 infection (Biobank) Biobanks Patrik Medstrand Lund University 2020 - 2021
A biomarker-based approach to rapidly identify COVID-19 patients at high risk of severe disease and mortality at 3 emergency departments in Region Skåne Biobanks Toralph Ruge Lund University 2020 - 2021
Simple and cheap remote test for infection based on HCR Diagnostics for virus Björn Högberg Karolinska Institute 2020 - 2021
COVID-19 screening test design Diagnostics for virus Masood Kamali-Moghaddam Uppsala University 2020 - 2021
iLACO-Sweden Diagnostics for virus Vicent Pelechano Karolinska Institute 2020 - 2021
Extraction-free high-sensitive RT assay for SARS-CoV-2 RNA detection Diagnostics for virus Björn Reinius Karolinska Institute 2020 - 2021
RCA-COVID-DIA Diagnostics for virus Mats Nilsson Stockholm University 2020 - 2021
COVseq – Developing COVseq for mass-scale SARS-CoV-2 sequencing Viral sequence evolution Nicola Crosetto Karolinska Institute 2020 - 2021
A community resource for SARS-CoV-2 structure, interactome and evolution Viral sequence evolution Arne Elofsson Stockholm University 2020 - 2021
Rapid cDNA and direct RNA sequencing of SARS-CoV-2 using Oxford Nanopore Viral sequence evolution Lars Feuk Uppsala University 2020 - 2021
Analysis of essential genes and validity as drug targets Viral sequence evolution Tomas Nyman Stockholm University 2020 - 2021
Optimized expression of the SARS-Cov-2 Spike protein in mammalian cells for serology testing and functional studies High-throughput and high-contents serology Fredrik Sterky University of Gothenburg 2020 - 2021
Production of SARS-CoV-2 surface proteins in HEK293 cells* High-throughput and high-contents serology Juni Andréll Stockholm University 2020 - 2021
Biological investigations of Covid-19 in cancer patients High-throughput and high-contents serology Gunilla Enblad Uppsala University 2020 - 2021
Peptides for serological test of COVID-19 antibodies and as molecular tools High-throughput and high-contents serology Ulf Göransson Uppsala University 2020 - 2021
Seroprevalence and predictors of COVID-19 disease severity in two areas of Sweden High-throughput and high-contents serology Anne Lindberg Umeå University 2020 - 2021
Large-scale production of a bio-safe antigen of COVID-19 and chimeric bat coronaviruses High-throughput and high-contents serology Kenta Okamoto Uppsala University 2020 - 2021
Translational serology for a population-wide assessment of Covid19 immunity High-throughput and high-contents serology Jochen Schwenk KTH Royal Institute of Technology 2020 - 2021
Multiplex analysis of immune response against Covid-19 High-throughput and high-contents serology Sofia Hober KTH Royal Institute of Technology 2020 - 2021
Rapid development of novel antibody assays diagnosing Covid-19 High-throughput and high-contents serology Jan-Åke Liljeqvist University of Gothenburg 2020 - 2021
Human antibodies against the SARS-CoV-2 spike protein High-throughput and high-contents serology Mats Ohlin Lund University 2020 - 2021
Characterization of the B cell response during SARS-CoV-2 infection High-throughput and high-contents serology Karin Loré Karolinska Institute 2020 - 2021
PLA-based large-scale analysis of Corona virus immunity High-throughput and high-contents serology Ulf Landegren Uppsala University 2020 - 2021
Neutralizing human B-cell derived monoclonal antibodies to SARS-CoV-2 High-throughput and high-contents serology Pontus Nordenfelt Lund University 2020 - 2021
SICoV – Serological Investigations on SARS-CoV-2 and other coronaviruses – improveddiagnostics and knowledge High-throughput and high-contents serology Åke Lundkvist Uppsala University 2020 - 2021
Covid-19 patients Biomarkers and systems biology Jacob Odeberg KTH Royal Institute of Technology 2020 - 2021
Prediction of severe disease in Covid-19 Biomarkers and systems biology Lars-Magnus Andersson University of Gothenburg 2020 - 2021
Taking back the control of the SARS-CoV2 antiviral immune response as a mean to neutralize the COVID19 disease pathogenicity Biomarkers and systems biology Marie Larsson Linköping University 2020 - 2021
Systems immunology analyses of the cytokine storm in COVID-19 Biomarkers and systems biology Petter Brodin Karolinska Institute 2020 - 2021
Establishing a biobank of clinical specimens for studying evolution of viral diversity and development of immune response, including inflammation, seroprevalence and protective antibodies, in SARS-Cov2 infection (Research project) Biomarkers and systems biology Patrik Medstrand Lund University 2020 - 2021
Dynamics and longevity of the specific adaptive immune response in COVID-19 patient Biomarkers and systems biology Davide Angeletti University of Gothenburg 2020 - 2021
Immediate molecular response to SARS-CoV-2 infection Host cell systems biology and targets Jonas Klingström Karolinska Institute 2020 - 2021
Mapping SARS-CoV-2 host-pathogen interactions for drug repurposing Host cell systems biology and targets Ylva Ivarsson Uppsala University 2020 - 2021
Viral-host interaction of SARS-CoV-2 protein corona Host cell systems biology and targets Maria Pernemalm Karolinska Institute 2020 - 2021
Profiling of host proteins associated to the envelope of SARS-CoV-2 Host cell systems biology and targets Claudia Fredolini KTH Royal Institute of Technology 2020 - 2021
Genetic screens to identify novel determinants of SARS-CoV-2 infection Host cell systems biology and targets Oscar Fernandez-Capetillo Karolinska Institute 2020 - 2021
Cellular thermal shift assay (CETSA) to identify host factors involved in SARS-CoV-2 entry and replication Host cell systems biology and targets Leo Hanke Karolinska Institute 2020 - 2021
Identification of host factors targeted by coronaviruses by Thermal proteome profiling Host cell systems biology and targets Oscar Fernandez-Capetillo Karolinska Institute 2020 - 2021
Creating synthetic biology tools to reveal the determinants of SARS-CoV-2 interactions with host cells Host cell systems biology and targets Erdinc Sezgin Karolinska Institute 2020 - 2021
Human precision cut lung slices as an ex vivo model for studying SARS-CoV2 infection and identifying potential therapies Host cell systems biology and targets Darcy Wagner Lund University 2020 - 2021
Identifying the Achilles heel of SARS-CoV-2 by using gene scissors Host cell systems biology and targets Claudia Kutter KTH Royal Institute of Technology 2020 - 2021
NEVERMORE COVID – Establishing a drug discovery platform for corona virus disease Drug discovery and repurposing of drugs Kristian Sandberg Uppsala University 2020 - 2021
A high-quality drug repurposing set Drug discovery and repurposing of drugs Anna-Lena Gustavsson Karolinska Institute 2020 - 2021
Multi-level profiling of Coronavirus-infected cells by combining Viral Entry Assays, Cell Painting, and DrugSEQ Drug discovery and repurposing of drugs Ola Spjuth Uppsala University 2020 - 2021
Spatial single cell mapping of SARS-CoV-2 interacting host proteins for quick and targeted drug repurposing Drug discovery and repurposing of drugs Charlotte Stadler KTH Royal Institute of Technology 2020 - 2021
FragCor – Fragment based NMR screen targeting SARS-Cov-2 proteins Drug discovery and repurposing of drugs Göran Karlsson University of Gothenburg 2020 - 2021
An adaptable therapeutic technology platform to treat SARS-CoV infections in immune suppressed individuals Drug discovery and repurposing of drugs Sara Mangsbo Uppsala University 2020 - 2021
Rapid testing for treatment of Covid-19 Drug discovery and repurposing of drugs Kristina Nyström Sahlgrenska University Hospital 2020 - 2021
Discovery of SARS-CoV-2 Inhibitors by Virtual Screening of Ultra-large Chemical Space Drug discovery and repurposing of drugs Jens Carlsson Uppsala University 2020 - 2021
Chemographic characterization of compounds binding to seven identified molecular targets from SARS-CoV-2 Drug discovery and repurposing of drugs Anders Backlund Uppsala University 2020 - 2021
Distributed computing to generate the druggable conformational ensemble of sars-cov-2 proteins Drug discovery and repurposing of drugs Lucie Delemotte KTH Royal Institute of Technology 2020 - 2021
ARS-CoV-2 in sewage water as a tool for monitoring the potential circulation of the viruses in the population and rate of infections (SARS-CoV-2) Environmental virus profiling Zeynep Cetecioglu Gurol KTH Royal Institute of Technology 2020 - 2021
Sewage as a proxy for SARS-CoV2 prevalence Environmental virus profiling Maja Malmberg Swedish Agricultural University 2020 - 2021
Detection, monitoring and genetic evaluation of SARS-CoV2 in wastewater treatment plants Environmental virus profiling Anna J. Székely Uppsala University 2020 - 2021
Surface persistence and SARS-CoV-2 exposure in the Stockholm Subway Environmental virus profiling Klas Udekwu Swedish Agricultural University 2020 - 2021
A multi-level digital twin framework for Covid-19: from mechanisms of disease ethiology, to clinical decision-support and epidemiology Data-driven research models and AI Gunnar Cedersund Linköping University 2020 - 2021
Building a platform with AI models, datasets and web applications for fighting COVID-19 Data-driven research models and AI Emma Lundberg KTH Royal Institute of Technology 2020 - 2021
Artificial intelligence-based knowledge curation to direct COVID-19 research and public health efforts Data-driven research models and AI Sonja Aits Lund University 2020 - 2021
COVID-19 – a population-based project of ICU patients Data-driven research models and AI Emma Larsson (will be combined with project below) Karolinska Institute 2020 - 2021
Characterization of ICU treated COVID patients in Sweden Data-driven research models and AI Jonathan Grip (will be combined with project above) Karolinska Institute 2020 - 2021
Rapid testing of SARS-Cov-2 in national coordination with health care Program for SARS-CoV-2 virus testing Lars Engstrand Karolinska Institute 2020 - 2021
Development of high-throughput serology testing capability Program for SARS-CoV-2 virus testing Peter Nilsson, Sophia Hober KTH Royal Institute of Technology 2020 - 2021
Sampling of COVID-19 patients for analysis of disease pathogenesis Program for SARS-CoV-2 virus testing Hans-Gustaf Ljunggren Karolinska University Hospital 2020 - 2021

NordForsk

nordforsk.org

Project title Principal investigator PI affiliation Duration
Addressing the smoking paradox in the etiology of COVID-19 through population-based studies Maria Rosaria Galanti Karolinska Institute 2020 - 2022
Data streams and mathematical modelling pipelines to support preparedness and decision making for COVID-19 and future pandemics Tom Britton Stockholm University 2020 - 2022

Vinnova

vinnova.se

Project title Principal investigator PI affiliation Duration
Antibodies against SARS-CoV-2 verification of commercially available assays and a nuanced sustainable approach Anna Fogdell-Hahn Karolinska Institute 2020-07-01 - 2021-06-30
Identification of epitopes on SARS-CoV-2 viral particles for rapid development of neutralizing antibodies Owe Orwar Oblique Therapeutics AB 2020-09-01 - 2021-12-31
Validation of a fast and effective Corona diagnostic test for the healthcare system Yalda Bogestål RISE Research Institutes of Sweden 2020-05-11 - 2020-10-30
Targeting the SARS-CoV-2 spike protein to achieve hyperimmunicity and reduce infectivity Rickard Nordén Angered Hospital 2020-10-01 - 2021-03-31
SARS-Cov-2 sensor for rapid sensitive virus detection Börje Sellergren SureCapture Technologies AB 2020-07-01 - 2021-06-30
Evaluating therapeutic potential of integrin 10-selected MSCs in treatment of COVID-19 (ARDS) Caroline Ehrencrona Xintela AB 2020-05-08 - 2020-11-30

Horizon 2020

ec.europa.eu

Project title Principal investigator PI affiliation Duration
Fighting-off coronavirus (SARS-CoV-2) with broad-spectrum antivirals: establishing animal viral challenge model Anna-Lena Spetz Stockholm University 2020-04-01 - 2022-03-31
Antibody therapy against coronavirus (COVID-19) Qiang Pan Hammarström, Harold Marcotte, Lennart Hammarström Karolinska Institute 2020-04-01 - 2022-03-31
Rapid therapy development through Open Coronavirus Vaccine Platform Matti Sällberg, Gustaf Ahlén Karolinska Institute 2020-04-01 - 2022-03-31
Nanobodies and antibodies against 2019-nCoV Benjamin Murrell, Gerald McInerney, Gunilla Karlsson Hedestam Karolinska Institute 2020-04-01 - 2022-03-31