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Data i fokus

“Data i fokus” notiserna visar nyligen publicerade dataset rörande COVID-19 och SARS-CoV-2 av forskare affilierade till ett svenskt lärosäte. Målet är att lyfta fram öppen forskning, öppna data och att möjliggöra återanvändning av forskningsdata i framtida forskning. Om du har publicerat data som du skulle vilja visa upp i datanotiserna, skicka ett förslag till oss.

    Svensk översättning för de engelska texterna kommer inom kort.
Database of COVID-19 sample collections and biobanks in Sweden launched
Database of COVID-19 sample collections and biobanks in Sweden launched

2021-02-24

In collaboration with Biobank Sweden, today we are launching a new section of the portal: the Swedish COVID-19 Sample Collection Database. The database allows to search for available biobank sample collections relevant for COVID-19 research.
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Bevacizumab treatment beneficial for patients with severe COVID-19
Bevacizumab treatment beneficial for patients with severe COVID-19

2021-02-18

A recently published clinical study investigating bevacizumab, a humanized anti-VEGF monoclonal antibody, offers promising results in fighting severe COVID-19. Treatment progress data and analysis code were shared publicly.
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Nanobodies promising new therapeutics for treatment of SARS CoV-2
Nanobodies promising new therapeutics for treatment of SARS CoV-2

2021-02-16

A recently published study characterizes the mechanisms by which nanobodies neutralize or prevent of infection in molecular detail. Crystallographic coordinates, cryo-EM density maps, and atomic coordinates were deposited to public databases.
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Data on COVID-19 testing in Uppsala County and dashboard with maps, trends and more now available
Data on COVID-19 testing in Uppsala County and dashboard with maps, trends and more now available

2021-02-11

The data portal is now launching a page with the CRUSH Covid dashboard with an option to download data on COVID-19 testing in each postal code of Uppsala County.
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Mechanism of entry used by human species D adenoviruses proving important for COVID-19 vaccine development
Mechanism of entry used by human species D adenoviruses proving important for COVID-19 vaccine development

2021-01-18

New study identifies a noncanonical entry mechanism used by human adenoviruses, important for development of adenovirus-based vaccine vectors. The reported X-ray structural data was made available through the Protein Data Bank.
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A novel approach to discover and characterize broad-spectrum antivirals
A novel approach to discover and characterize broad-spectrum antivirals

2020-12-18

Newly discovered antiviral compounds showed broad-range antiviral activity against pathogenic RNA viruses such as SARS-CoV-2. The authors share data freely in open repositories.
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Pathogenesis of hyperinflammatory syndrome associated with COVID-19 in children
Pathogenesis of hyperinflammatory syndrome associated with COVID-19 in children

2020-12-07

Multiple autoantibodies and specific cytokines could be involved in the pathogenesis of MIS-C associated with COVID-19. Data and code made available in open repositories.
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An alpaca-derived nanobody can potently neutralize SARS-CoV-2
An alpaca-derived nanobody can potently neutralize SARS-CoV-2

2020-11-27

Leo Hanke and colleagues identified a SARS-CoV-2 RBD-specific single domain antibody fragment, Ty1, that potently neutralizes the virus. Ty1 should now be further investigated as a candidate for antiviral therapy.
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Synthetic nanobodies are easy to produce and can effectively neutralize SARS-CoV-2
Synthetic nanobodies are easy to produce and can effectively neutralize SARS-CoV-2

2020-11-24

Recently published study demonstrates that it is possible to select highly specific binders with neutralizing activity against SARS-CoV-2 from a synthetic nanobody library in a short timeframe.
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MAIT cell activation and dynamics studied in relation to COVID-19 disease severity
MAIT cell activation and dynamics studied in relation to COVID-19 disease severity

2020-11-18

Tiphaine Parrot and colleagues studied changes in conventional and unconventional T cell subsets in patients with various disease severity using flow cytometry. The results were published along with the data.
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Crystal structure of SARS CoV-2 nsp-10 - a potential drug target for COVID-19
Crystal structure of SARS CoV-2 nsp-10 - a potential drug target for COVID-19

2020-11-03

A study by Rogstam and colleagues published along with the crystal structure of SARS CoV-2 non-structural protein 10 in the Protein Data Bank provides a starting point for structure-guided drug discovery and design.
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Bayesian model for estimating the impact of mobility patterns on COVID-19 infection
Bayesian model for estimating the impact of mobility patterns on COVID-19 infection

2020-10-23

Patrick Bryant and Arne Elofsson shared code and instructions for modelling COVID-19 development using MCMC simulations based on mobile phone mobility data from Google mobility reports.
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Nu publiceras den första studien baserad på data från storskalig serologisk analys vid SciLifeLab
Nu publiceras den första studien baserad på data från storskalig serologisk analys vid SciLifeLab

2020-10-15

Studien utgår endast från en bråkdel av den mängd SARS-CoV-2-data som samlats in av ScilifeLab Autoimmunity and Serology profiling facility.
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Neandertalgenom kopplas till ökad risk för svår COVID-19 infektion i studie som använder datadriven forskningsmetod
Neandertalgenom kopplas till ökad risk för svår COVID-19 infektion i studie som använder datadriven forskningsmetod

2020-10-02

Studie av Hugo Zeberg and Svante Pääbo som är helt baserad på öppen data publiceras med fri tillgång i Nature.
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Studie av covid-19 RT-PCR test som inte kräver RNA-extraktion publicerad med data
Studie av covid-19 RT-PCR test som inte kräver RNA-extraktion publicerad med data

2020-10-01

Data från artiklen är fritt tillgänglig via Nature Communications och kod finns på Github.
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Ny sida med statistik över SARS-CoV-2-antikroppstester som utförts av SciLifeLab
Ny sida med statistik över SARS-CoV-2-antikroppstester som utförts av SciLifeLab

2020-09-30

Nu lanserar vi en ny sida med grafer som visar statistik över de SARS-CoV-2-antikroppstester som utförts vid SciLifeLab Autoimmunity and Serology profiling facility.
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