COVID-19

Below is an overview of various sections of The Swedish COVID-19 & Pandemic Preparedness Portal where information about research data and resources relevant to COVID-19 can be found. For a short background on this topic below, see the description below.

Data highlights (33)

COVID-19 Infectious diseases

Large scale immunofluorescence to explore the host cell response to SARS-CoV-2 infection

2022-04-25

Expression of 602 host proteins were evaluated in populations of infected and non-infected cells using immunofluorescence. ≈75,000 images have been published as a resource for further studies.
Read more

COVID-19 Infectious diseases

Direct RT-PCR used to monitor Omicron BA.1/BA.2 variant transition in Sweden

2022-04-04

Lentini and collegues used direct RT-PCR to show the transition from Omicron BA.1 to sub-variant BA.2 in Sweden Jan-March 2022. New Preprint from Reinius lab which shares data and code.
Read more

COVID-19 Infectious diseases

Interactions between fragments and SARS-CoV-2 nsp10 provide insight into the viral replications

2022-03-01

Interactions between fragments and SARS-CoV-2 nsp10 have been successfully identified and characterised by Kozielski and colleagues. Data shared on the Protein Data Bank and Zenodo.
Read more

See all data highlights on COVID-19 (33)

Dashboards (6)

SciLifeLab Autoimmunity and Serology profiling facility SARS-CoV-2 antibody test statistics

The amount of SARS-CoV-2 virus in wastewater across Sweden

The administration and study of COVID-19 vaccines in Sweden

Post COVID-19 condition in Sweden: statistics, research projects, and available data

See all dashboards on COVID-19 (6)

Sample collections (35)

Name	Type	Size	Materials
Dalarna biobank (forskningsprov och nyinsamlade prov): SARS-CoV-2 PCR positiva Dalarna	Healthcare sample collection	1000 - 10.000	Nasal swab Throat swab
Gävleborg biobank: Klinisk mikrobiologi	Healthcare sample collection	1000 - 10.000	Nasal swab Serum Throat swab Other
Halland biobank: Patologen Halland	Healthcare sample collection	100 - 1000	Tissue (stained sections/slides) Tissue (paraffin preserved)

See all sample collections on COVID-19 (35)

Ongoing research projects (117)

Project title	Funder	Topics
The COMMUNITY Study - COVID-19 Biomarker and Immunity Study Host institute: Karolinska Institute / Danderyd Hospital Principal investigator: Charlotte Thålin Project: The COMMUNITY Study - COVID-19 Biomarker and Immunity Study Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Charlotte Thålin Host institute: Karolinska Institute / Danderyd Hospital Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases
Validation and characterisation of novel plasma biomarkers for risk prediction and stratification of COVID-19 patients Host institute: KTH Royal Institute of Technology Principal investigator: Jacob Odeberg Project: Validation and characterisation of novel plasma biomarkers for risk prediction and stratification of COVID-19 patients Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Jacob Odeberg Host institute: KTH Royal Institute of Technology Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases
NEVERMORE COVID – Establishing a drug discovery platform for corona virus disease Host institute: Uppsala University Principal investigator: Kristian Sandberg Project: NEVERMORE COVID – Establishing a drug discovery platform for corona virus disease Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Kristian Sandberg Host institute: Uppsala University Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases

See all ongoing research projects on COVID-19 (117)

Open funding opportunities (2)

Call title	Deadline	Funder	Topics
Project grant for research into pandemics and their effects on society and public health The purpose of the project grant is to give researchers the freedom to formulate by themselves the research concept, method and implementation, and to solve a specific research task within a … Project grant for research into pandemics and their effects on society and public health Funder: Swedish Research Council Submission opens: September 20, 2022 Submission deadline: August 17, 2022 Call description: The purpose of the project grant is to give researchers the freedom to formulate by themselves the research concept, method and implementation, and to solve a specific research task within a limited period. This is a project grant with focus, aimed at supporting research into pandemics and their effects on society and public health. See call website for more information	August 17, 2022	Swedish Research Council	COVID-19Infectious diseasesAntibiotic resistance
Societal Security Beyond COVID-19 Projects in this call can address the medium to long-term effects for individuals and groups, for Nordic societies, and for the Nordic community, of the COVID-19 pandemic within the thematic … Societal Security Beyond COVID-19 Funder: NordForsk Submission deadline: June 8, 2022 Funding amount: Maximum 9 000 000 NOK Funding period: 3–4 years Eligible applicant: Individual researcher Decision date: Late 2022 Call description: Projects in this call can address the medium to long-term effects for individuals and groups, for Nordic societies, and for the Nordic community, of the COVID-19 pandemic within the thematic framework of the call. Emphasis is placed on linking research and practice, and the involvement of various types of end users is encouraged to help strengthen the knowledge base for practice and for research-informed policy. The overarching theme of the call is to explore the medium to long-term consequences beyond the COVID-19 pandemic as they relate to societal security and the notion of a Nordic community, and how the Nordic countries can evolve together – or not together – for the future. See call website for more information	June 8, 2022	NordForsk	COVID-19

See all open funding opportunities on COVID-19 (2)

Background

Coronavirus disease (COVID-19) is an infectious disease caused by the novel SARS-CoV-2 virus. Since its start in early 2020, the COVID-19 pandemic has challenged societies worldwide. While most people infected experience mild to moderate respiratory illness and recover without treatment, the disease can be severe or fatal. Advanced age and underlying medical conditions, such as cardiovascular disease, diabetes, cancer, or chronic respiratory disease, have all been associated with increased risk of severe outcome. However, anyone independent of age or comorbidities is at risk for COVID-19 severe disease outcome. As of March 2022, more than 200 million confirmed cases and over 4 million deaths have been reported.

The research community worldwide has, in an unprecedented way, focused their research efforts towards investigating the novel SARS-CoV-2 virus and variants, as well as variants of concern (VoCs) have emerged more, and the impact of COVID-19 on human body. These contributions from the research community have been a crucial part of the rapid vaccine development. Vaccines are today the cornerstone of global pandemic management. Whilst vaccines were rolled out in record time and have proven very effective diminishing the risk of severe COVID-19 disease and death, many research questions remain. Although we are now entering a more endemic period, COVID-19 is a serious health threat worldwide. Research and lessons learned are crucial for early detection of outbreaks, ability to rapidly identify potential new SARS CoV-2 variants of concern, development of additional treatment options, and future pandemic preparedness. There is still an uncertainty regarding the duration of vaccine protection and effectiveness of booster doses. In addition, vaccine escape has been shown by several current VoCs which could make vaccines less efficient.