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COVID-19

Below is an overview of various sections of The Swedish COVID-19 & Pandemic Preparedness Portal where information about research data and resources relevant to COVID-19 can be found. For a short background on this topic below, see the description below.

Data highlights (34)

A wider variety of data sources contribute to better spatio-temporal predictions of COVID-19 test positivity COVID-19 Infectious diseases
A wider variety of data sources contribute to better spatio-temporal predictions of COVID-19 test positivity

2022-11-22

Van Zoest et al (2022) developed and evaluated the performance of four different statistical single models and one ensemble model to predict trends in COVID-19 test positivity. Data are shared openly in GitHub.
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Data-driven research shows that Neanderthal gene connected to severity of COVID-19 (Update) COVID-19 Infectious diseases
Data-driven research shows that Neanderthal gene connected to severity of COVID-19 (Update)

2022-10-03

Study by Hugo Zeberg and Svante Pääbo fully based on openly available data published open access in Nature.

Now a Nobel Prize winner!!
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Direct RT-PCR used to monitor Omicron BA.1/BA.2 variant transition in Sweden (Update) COVID-19 Infectious diseases
Direct RT-PCR used to monitor Omicron BA.1/BA.2 variant transition in Sweden (Update)

2022-08-15

Lentini and collegues used direct RT-PCR to show the transition from Omicron BA.1 to sub-variant BA.2 in Sweden Jan-March 2022. New Preprint from Reinius lab which shares data and code.
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Dashboards (6)


Sample collections (35)

Name Type Size Materials
Dalarna biobank (forskningsprov och nyinsamlade prov):
SARS-CoV-2 PCR positiva Dalarna
Healthcare sample collection 1000 - 10.000 Nasal swab Throat swab
Gävleborg biobank:
Klinisk mikrobiologi
Healthcare sample collection 1000 - 10.000 Nasal swab Serum Throat swab Other
Halland biobank:
Patologen Halland
Healthcare sample collection 100 - 1000 Tissue (stained sections/slides) Tissue (paraffin preserved)

Ongoing research projects (56)

Project title Funder Topics
Immunological correlates of protection in COVID-19 disease and after COVID-19 vaccination

Host institute: Karolinska Institute
Principal investigator: Anna Smed Sörensen

Swedish Research Council COVID-19Infectious diseases
Stochastic modelling of epidemic outbreaks - post Covid-19

Host institute: Stockholm University
Principal investigator: Tom Britton

Swedish Research Council COVID-19Infectious diseases
Wuhan Interaction with Stockholm Evidence-based Research (WISER) project on health perspectives in the older population facing the SARS-CoV-2 outbreak

Host institute: Karolinska Institute
Principal investigator: Sara Hägg

Swedish Research Council COVID-19Infectious diseases

Open funding opportunities (7)

Call title Deadline Funder Topics
The Foundation distributes grants for research or travel related to the treatment of infectious diseases with antibacterial, antiviral, antimycotic or antiparasitic agents. The assets of the …
February 1, 2023 Scandinavian Society of Antimicrobial Chemotherapy Foundation Infectious diseasesGeneral
Researchers are invited to submit any proposal that can be advanced by access to at least one of ISIDORe's services, falls under topics defined in the Scope (see funding link for details), …
February 7, 2023 ISIDORe Infectious diseasesGeneral
Researchers are invited to submit any proposal that can be advanced by access to at least one of ISIDORe's services, falls under topics defined in the Scope (see funding link for details), …
January 1, 2025 ISIDORe Infectious diseasesGeneral

Background

Coronavirus disease (COVID-19) is an infectious disease caused by the novel SARS-CoV-2 virus. Since its start in early 2020, the COVID-19 pandemic has challenged societies worldwide. While most people infected experience mild to moderate respiratory illness and recover without treatment, the disease can be severe or fatal. Advanced age and underlying medical conditions, such as cardiovascular disease, diabetes, cancer, or chronic respiratory disease, have all been associated with increased risk of severe outcome. However, anyone independent of age or comorbidities is at risk for COVID-19 severe disease outcome. As of March 2022, more than 200 million confirmed cases and over 4 million deaths have been reported.

The research community worldwide has, in an unprecedented way, focused their research efforts towards investigating the novel SARS-CoV-2 virus and variants, as well as variants of concern (VoCs) have emerged more, and the impact of COVID-19 on human body. These contributions from the research community have been a crucial part of the rapid vaccine development. Vaccines are today the cornerstone of global pandemic management. Whilst vaccines were rolled out in record time and have proven very effective diminishing the risk of severe COVID-19 disease and death, many research questions remain. Although we are now entering a more endemic period, COVID-19 is a serious health threat worldwide. Research and lessons learned are crucial for early detection of outbreaks, ability to rapidly identify potential new SARS CoV-2 variants of concern, development of additional treatment options, and future pandemic preparedness. There is still an uncertainty regarding the duration of vaccine protection and effectiveness of booster doses. In addition, vaccine escape has been shown by several current VoCs which could make vaccines less efficient.