COVID-19

Below is an overview of various sections of The Swedish COVID-19 & Pandemic Preparedness Portal where information about research data and resources relevant to COVID-19 can be found. For a short background on this topic below, see the description below.

Data highlights (33)

COVID-19 Infectious diseases

Data-driven research shows that Neanderthal gene connected to severity of COVID-19 (Update)

2022-10-03

Study by Hugo Zeberg and Svante Pääbo fully based on openly available data published open access in Nature.

Now a Nobel Prize winner!!
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COVID-19 Infectious diseases

Direct RT-PCR used to monitor Omicron BA.1/BA.2 variant transition in Sweden (Update)

2022-08-15

Lentini and collegues used direct RT-PCR to show the transition from Omicron BA.1 to sub-variant BA.2 in Sweden Jan-March 2022. New Preprint from Reinius lab which shares data and code.
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COVID-19 Infectious diseases

Large scale immunofluorescence to explore the host cell response to SARS-CoV-2 infection

2022-04-25

Expression of 602 host proteins were evaluated in populations of infected and non-infected cells using immunofluorescence. ≈75,000 images have been published as a resource for further studies.
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See all data highlights on COVID-19 (33)

Dashboards (6)

SciLifeLab Autoimmunity and Serology profiling facility SARS-CoV-2 antibody test statistics

The amount of SARS-CoV-2 virus in wastewater across Sweden

The administration and study of COVID-19 vaccines in Sweden

Post COVID-19 condition in Sweden: statistics, research projects, and available data

See all dashboards on COVID-19 (6)

Sample collections (35)

Name	Type	Size	Materials
Dalarna biobank (forskningsprov och nyinsamlade prov): SARS-CoV-2 PCR positiva Dalarna	Healthcare sample collection	1000 - 10.000	Nasal swab Throat swab
Gävleborg biobank: Klinisk mikrobiologi	Healthcare sample collection	1000 - 10.000	Nasal swab Serum Throat swab Other
Halland biobank: Patologen Halland	Healthcare sample collection	100 - 1000	Tissue (stained sections/slides) Tissue (paraffin preserved)

See all sample collections on COVID-19 (35)

Ongoing research projects (117)

Project title	Funder	Topics
The COMMUNITY Study - COVID-19 Biomarker and Immunity Study Host institute: Karolinska Institute / Danderyd Hospital Principal investigator: Charlotte Thålin Project: The COMMUNITY Study - COVID-19 Biomarker and Immunity Study Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Charlotte Thålin Host institute: Karolinska Institute / Danderyd Hospital Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases
Validation and characterisation of novel plasma biomarkers for risk prediction and stratification of COVID-19 patients Host institute: KTH Royal Institute of Technology Principal investigator: Jacob Odeberg Project: Validation and characterisation of novel plasma biomarkers for risk prediction and stratification of COVID-19 patients Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Jacob Odeberg Host institute: KTH Royal Institute of Technology Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases
NEVERMORE COVID – Establishing a drug discovery platform for corona virus disease Host institute: Uppsala University Principal investigator: Kristian Sandberg Project: NEVERMORE COVID – Establishing a drug discovery platform for corona virus disease Funder: SciLifeLab / Knut and Alice Wallenberg Foundation Principal investigator: Kristian Sandberg Host institute: Uppsala University Duration: 2020-01-01 – 2022-12-31 More information about the project	SciLifeLab / Knut and Alice Wallenberg Foundation	COVID-19Infectious diseases

See all ongoing research projects on COVID-19 (117)

Open funding opportunities (2)

Call title	Deadline	Funder	Topics
Welfare among Children and Young People in the Post-Pandemic Nordics The overall objective of the call is to support and accelerate cutting edge Nordic research with high potential for renewal and impact on the welfare among children and young people in the … Welfare among Children and Young People in the Post-Pandemic Nordics Funder: Swedish Research Council Submission opens: September 16, 2022 Submission deadline: December 8, 2022 Funding amount: NOK 11 million is the maximum amount of funding that may be sought Funding period: 3-4 years Eligible applicant: The research project must include partners from research performing organisations in at least three Nordic countries Decision date: Shortly after May 2023 Call description: The overall objective of the call is to support and accelerate cutting edge Nordic research with high potential for renewal and impact on the welfare among children and young people in the post-pandemic Nordics. The call has an emphasis on education, wellbeing, mental health, and living conditions of children and young people. See call website for more information	December 8, 2022	Swedish Research Council	COVID-19General
SARS-COV-2 & COVID‑19 Your request for free of charge transnational access to ISIDORe services for supporting and advancing your research must be focused on one of; surveillance & epidemic risk management, … SARS-COV-2 & COVID‑19 Funder: ISIDORe Submission opens: May 15, 2022 Submission deadline: January 1, 2025 Funding amount: Funding will be available for as long as it remains available. Call provides access to ISIDORe services, not a given monetary amount. Call description: Your request for free of charge transnational access to ISIDORe services for supporting and advancing your research must be focused on one of; surveillance & epidemic risk management, understanding SARS-CoV- 2 & COVID-19, diagnostics, therapeutics, vaccines, or social sciences & epidemiology. See call website for more information	January 1, 2025	ISIDORe	Infectious diseasesCOVID-19

See all open funding opportunities on COVID-19 (2)

Background

Coronavirus disease (COVID-19) is an infectious disease caused by the novel SARS-CoV-2 virus. Since its start in early 2020, the COVID-19 pandemic has challenged societies worldwide. While most people infected experience mild to moderate respiratory illness and recover without treatment, the disease can be severe or fatal. Advanced age and underlying medical conditions, such as cardiovascular disease, diabetes, cancer, or chronic respiratory disease, have all been associated with increased risk of severe outcome. However, anyone independent of age or comorbidities is at risk for COVID-19 severe disease outcome. As of March 2022, more than 200 million confirmed cases and over 4 million deaths have been reported.

The research community worldwide has, in an unprecedented way, focused their research efforts towards investigating the novel SARS-CoV-2 virus and variants, as well as variants of concern (VoCs) have emerged more, and the impact of COVID-19 on human body. These contributions from the research community have been a crucial part of the rapid vaccine development. Vaccines are today the cornerstone of global pandemic management. Whilst vaccines were rolled out in record time and have proven very effective diminishing the risk of severe COVID-19 disease and death, many research questions remain. Although we are now entering a more endemic period, COVID-19 is a serious health threat worldwide. Research and lessons learned are crucial for early detection of outbreaks, ability to rapidly identify potential new SARS CoV-2 variants of concern, development of additional treatment options, and future pandemic preparedness. There is still an uncertainty regarding the duration of vaccine protection and effectiveness of booster doses. In addition, vaccine escape has been shown by several current VoCs which could make vaccines less efficient.