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Infectious diseases

Below is an overview of various sections of The Swedish COVID-19 & Pandemic Preparedness Portal where information about research data and resources relevant to Infectious diseases can be found. For a short background on this topic below, see the description below.

Data highlights (36)

Cryo-electron tomography allows new knowledge about poliovirus replication and assembly sites in situ Infectious diseases
Cryo-electron tomography allows new knowledge about poliovirus replication and assembly sites in situ

2022-12-19

Dahmane et al (2022) used Cryo-electron tomography to provide an integrated structural framework for multiple stages of the poliovirus life cycle. Data and code are shared openly.
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A wider variety of data sources contribute to better spatio-temporal predictions of COVID-19 test positivity COVID-19 Infectious diseases
A wider variety of data sources contribute to better spatio-temporal predictions of COVID-19 test positivity

2022-11-22

Van Zoest et al (2022) developed and evaluated the performance of four different statistical single models and one ensemble model to predict trends in COVID-19 test positivity. Data are shared openly in GitHub.
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Data-driven research shows that Neanderthal gene connected to severity of COVID-19 (Update) COVID-19 Infectious diseases
Data-driven research shows that Neanderthal gene connected to severity of COVID-19 (Update)

2022-10-03

Study by Hugo Zeberg and Svante Pääbo fully based on openly available data published open access in Nature.

Now a Nobel Prize winner!!
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Dashboards (6)


Sample collections (35)

Name Type Size Materials
Dalarna biobank (forskningsprov och nyinsamlade prov):
SARS-CoV-2 PCR positiva Dalarna
Healthcare sample collection 1000 - 10.000 Nasal swab Throat swab
Gävleborg biobank:
Klinisk mikrobiologi
Healthcare sample collection 1000 - 10.000 Nasal swab Serum Throat swab Other
Halland biobank:
Patologen Halland
Healthcare sample collection 100 - 1000 Tissue (stained sections/slides) Tissue (paraffin preserved)

Ongoing research projects (56)

Project title Funder Topics
Immunological correlates of protection in COVID-19 disease and after COVID-19 vaccination

Host institute: Karolinska Institute
Principal investigator: Anna Smed Sörensen

Swedish Research Council COVID-19Infectious diseases
Stochastic modelling of epidemic outbreaks - post Covid-19

Host institute: Stockholm University
Principal investigator: Tom Britton

Swedish Research Council COVID-19Infectious diseases
Wuhan Interaction with Stockholm Evidence-based Research (WISER) project on health perspectives in the older population facing the SARS-CoV-2 outbreak

Host institute: Karolinska Institute
Principal investigator: Sara Hägg

Swedish Research Council COVID-19Infectious diseases

Open funding opportunities (9)

Call title Deadline Funder Topics
The purpose of the grant is to support international collaboration in the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR). This is the 16th call within JPIAMR and has the …
March 14, 2023 JPIAMR Infectious diseasesAntibiotic resistance
The purpose of the grant is to support international collaboration in the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR). This is the 16th call within JPIAMR and has the …
March 7, 2023 JPIAMR Infectious diseasesAntibiotic resistance
The Foundation distributes grants for research or travel related to the treatment of infectious diseases with antibacterial, antiviral, antimycotic or antiparasitic agents. The assets of the …
February 1, 2023 Scandinavian Society of Antimicrobial Chemotherapy Foundation Infectious diseasesGeneral

Background

Infectious diseases are one of the most prominent threats to public health globally. Multiple types of organisms cause infectious disease, including bacteria (for example, urinary tract infections, tuberculosis), viruses (for example, the common cold, influenza, and coronaviruses), fungi (for example, ringworm), and parasitic organisms (for example, malaria).

Infectious diseases can spread directly or indirectly in multiple different ways. For example, they may spread through droplets in the air, by exchanging bodily fluids, and by consuming contaminated food. Infectious diseases can spread between humans (including from mother to unborn child) as well as between animals and humans.

The COVID-19 pandemic has highlighted exactly how detrimental coronaviruses can be to public health over the last 2+ years. However, many other infectious diseases have a significant, negative effect worldwide. Some examples of infectious agents affecting millions of people globally are Dengue fever, Ebola, HIV, Measles, Legionella, tuberculosis, West Nile fever, and Zika virus. Research into these infectious agents and efforts to monitor their spread took place before the COVID-19 pandemic, continued throughout, and will progress into the future. For example, Influenza is a seasonal airway infection that affects thousands of people in Sweden annually. Influenza can cause severe disease and possibly even lead to death in individuals where the immune response is compromised in some way (for example, in the elderly). The four subtypes of influenza (A, B, C, and D) are well known, but novel strains regularly emerge, and can result in outbreaks or even pandemics (for example, the Spanish flu). Given the potential negative effects of influenza on public health, continuous efforts are made to monitor its spread and to develop vaccines against novel strains. See the website of the Swedish Public Health Agency for more information related to influenza and how it is managed in Sweden (resources in Swedish).

It is clear then, that further work into known, emerging, and novel infectious diseases is warranted. In paticular, research is needed to elucidate their pathogenicity, the development of resistance to existing treatments (including antibiotic resistance), and to develop effective policies and treatments to minimise their impact. Further, surveillance is required to monitor their spread, as this will show when/where outbreaks occur and enable us to contain them.

For more information on how infectious diseases are monitored in Europe, see the European Centre for Disease Prevention and Control (ECDC) pages. For statistics regarding infectious diseases that are reported to the authorities in Sweden, see the Swedish Public Health Agency pages.